A Bill - Article I, Section 1 of the United States
Constitution is concise in its language, "All legislative powers herein
granted shall be vested in a Congress of the United States, which shall consist
of a Senate and House of Representatives."
It means a Bill has to be passed by both the Senate and the House of
Representatives so that President of the United States of America can sign it
and implement as a law.
A Rule or Federal Regulations - Please check the official links to get the explanation about the Rule making process.
http://www.regulations.gov/#!aboutProgram
http://www.regulations.gov/#!aboutProgram
Source: Wikipedia